Are you or a loved one looking for a sober living program? Give us a call! 424-327-4614

Are you or a loved one looking for a sober living program?  Give us a call!

Alcohol and Amoxicillin

Medically Reviewed by: Charley Allen

Table of Contents

Combining alcohol and prescription drugs can be risky. In general, doctors advise against drinking when taking medications. It is because mixing alcohol with drugs may raise the chance of dangerous side effects.

Individuals diagnosed with bacterial infections are curious whether they should abstain from alcohol if their doctor prescribes amoxicillin. Although mixing alcohol and amoxicillin is deemed safe, combining the two must be exercised with caution to prevent a potentially severe reaction.

What is Amoxicillin?  

Amoxicillin is a penicillin antibiotic used to treat bacterial infections such as tooth abscesses, urinary tract infections, skin infections, infections of the ears, nose, and throat, and chest infections, including pneumonia. It can also be used as a treatment for stomach ulcers caused by the bacteria H. pylori in combination with certain antibiotics and medications. Amoxicillin is not used for the treatment of viral or fungal infections.

1 Design for Recovery

Amoxicillin is one of the most commonly prescribed antibiotics frequently used in children to treat chest and ear infections. In taking amoxicillin safely, it is important to complete the whole course of therapy as advised by your medical practitioner. Despite feeling better, you should not skip or stop amoxicillin doses because doing so can lengthen the duration of your infection. You may also potentially develop resistance to the medication and other antibiotic treatment options. This implies that you might not be able to use amoxicillin to treat bacterial infections in the future.

The only way to obtain amoxicillin is through a prescription. It is available in capsule, chewable tablet, or liquid form. It can also be injected, however, this is typically done exclusively in hospitals. Amoxicillin treatments normally last a few days to a few weeks. The recommended dosage depends on your medical condition.

Amoxicillin Side Effects

Amoxicillin can have side effects, depending on the individual’s sensitivity to the drug.

2 Design for Recovery

Approximately one in ten individuals experience these common side effects. If the following most common side effects concern you or do not go away while taking the medication, speak to your doctor or pharmacist immediately:

  • Nausea
  • Diarrhea
  • Vomiting

Short-term Effects of Amoxicillin 

Since amoxicillin antibiotics are often taken as a short-term course, side effects should be minimal. In most instances, adverse symptoms disappear after an individual stops taking antibiotics. Short-term, non-life-threatening side effects, such as nausea, vomiting, and diarrhea, often subside in a matter of days or weeks.

Long-term Effects of Amoxicillin

Some individuals experience serious adverse effects, especially if they have a severe allergic reaction. For serious or persistent infections, such as osteomyelitis, an individual may need to take antibiotics for a longer amount of time. They have a higher chance of developing long-term issues as a result, including liver damage, nephritis, hemolytic anemia, and crystalluria (cloudy urine).

Call your medical practitioner or visit the nearest emergency room if you have any of the following severe reactions:

  • Difficulty breathing
  • Severe diarrhea that is bloody and lasts longer than four days, which may be accompanied by stomach pain
  • Joint or muscle soreness that develops after taking the medication for two days
  • A rash on the skin with circular red spots (may be less visible on brown or black skin)
  • Possible indicators of liver damage or gallbladder issues: the whites of your eyes or skin may appear yellow (may be less visible on brown or black skin); pale stool and dark urine
  • Bruises or changes in your skin tone

Taking Amoxicillin with Alcohol 

The FDA’s medication label for amoxicillin indicates no drug interactions with alcohol, which means that moderate alcohol consumption is safe when using amoxicillin. Amoxicillin and alcohol together won’t have a severe, long-lasting impact on your health.

3 Design for Recovery

It shouldn’t be a problem to have a glass of red wine with a meal. However, if you plan on consuming multiple glasses, you may be in danger. For instance, if you drink excessively, you may develop nausea and vomiting, which are common side effects of amoxicillin.

It can also lead to other adverse reactions like headaches and diarrhea and aggravate nausea and vomiting. It is important to avoid alcohol completely when taking antibiotics to ensure a quick recovery.

Risks of Mixing Amoxicillin with Alcohol 

Amoxicillin has no serious negative effects when combined with a moderate amount of alcoholic beverages. However, binge drinking alcohol while taking medicine may increase health risks, such as:

  • Your immune system will be weakened by alcohol, which might disrupt the effectiveness of amoxicillin. It will take you longer to recuperate from your illness because alcohol intake is known to delay healing and recovery.
  • Increased nausea is one of the negative side effects of amoxicillin. While using amoxicillin or other antibiotics, drinking alcohol might make these nauseating sensations worse.

4 Design for Recovery

To prevent affecting drug therapy, it is advised to avoid drinking alcohol when taking any prescription drug.

Side Effects of Mixing Amoxicillin with Alcohol

Alcohol and amoxicillin both have similar side effects, such as headache, nausea, vomiting, and diarrhea. You could be more vulnerable to such negative effects if you take both at once.

Some healthcare professionals may advise against alcohol intake since it may lead to dehydration and exacerbate symptoms of an underlying infection that is already being treated.

With that said, it is best to refrain from drinking alcohol when you are ill since alcohol interferes with your ability to recover from infections. 

Frequently Asked Questions 

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.

According to a study, combining amoxicillin and alcohol results in a decreased rate of absorption. This indicates that when alcohol is present, amoxicillin does not act as quickly as it should.

In other words, mixing amoxicillin with alcohol delays your system’s healing process.

While a moderate amount of alcohol is safe to consume while taking amoxicillin, heavy drinking will dehydrate you more and weaken your immune system, both of which can prolong the duration of your illness.

When you are unwell or still on antibiotics therapy, it is best to avoid alcohol consumption in order to heal faster.

Alcohol use and amoxicillin intake are generally considered safe. Even though moderate alcohol use does not affect drug efficacy, it can lower your energy and slow down your recovery from bacterial infection.

To be safe, avoid alcohol for 48 to 72 hours after you finish the last dose of amoxicillin. You should also wait until your illness has completely resolved before you drink alcohol to ensure your body’s ability to heal and recover.

Unlike other prescribed antibiotics, such as tinidazole and metronidazole, amoxicillin does not interact with meals or beverages, so you may continue your usual diet.

On the other hand, tinidazole, metronidazole, and several other antibiotics can result in a severe reaction when taken with alcohol.

Yes, you can drink alcohol while taking amoxicillin. Moderate drinking of alcoholic beverages is safe when you’re taking the drug. However, it is still safer to refrain from drinking alcohol while taking antibiotics and other medications.

Drinking alcohol may worsen the side effects of amoxicillin, such as a weakened immune system, making bacterial infections more difficult to cure.

If you have alcohol abuse and find it challenging to stop drinking, you may need professional treatment advice or assistance from alcohol rehab.

Read Further:

Ambien and Alcohol: A Deadly Combination

Heroin with Alcohol: A Dangerous Combination

Synthetic Marijuana and Alcohol: Long-term Dangers

Effects of Mixing Alcohol and Xanax

Ibuprofen and Alcohol: Is It Safe to Combine?

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.
  1. Mergenhagen, K. A., Wattengel, B. A., & Skelly, M. K., Clark. (2020). Fact versus Fiction: a Review of the Evidence behind Alcohol and Antibiotic Interactions. Antimicrobial agents and chemotherapy, 64(3), e02167-19.
  2. Amoxicillin. (2021, November 12). NHS.UK.
  3. Akhavan BJ, Khanna NR, Vijhani P. Amoxicillin. (2022, August 8). Amoxicillin. National Library of Medicine.
  4. Trevejo-Nunez, G., Kolls, J. K., & de Wit, M. (2015). Alcohol Use As a Risk Factor in Infections and Healing: A Clinician’s Perspective. Alcohol research: current reviews, 37(2), 177–184.
  5. Amoxicillin. (2022, January 15).
  6. Morasso, M. I., Hip, A., & Márquez, M. (1988). Amoxicillin kinetics and ethanol ingestion. International journal of clinical pharmacology, therapy, and toxicology, 26(9), 428–431.


Edited by: David Beasley

David Beasley - Design for Recovery

David Beasley is a certified RADT (Registered Alcohol/Drug Technician). David, moved to California from North Carolina after many failed attempts to get sober.

Medically Reviewed by: Charley Allen

Charley earned his Masters of Clinical Psychology from Antioch University, Los Angeles, and is a California Licensed Marriage and Family Therapist (LMFT).He teaches mindfulness to both adults and children in group setting such as schools, corporate workplaces, and medical treatment facilities.

We Can Help

Design for Recovery - Locations Pages Contact Form

Read More

Addiction & Recovery

Sober Living in Los Angeles - Design for Recovery

About Us

Design for Recovery empowers men struggling with addiction by providing 24/7 support, mentorship, and teaches them how to live healthy, fulfilling lives.

Chat with us on Facebook
relapse prevention

Are you or a loved one struggling with addiction? We can help!

Our advisors are waiting for your call: 424-327-4614

Reach out to us today.

Design For Recovery is committed to helping you or your loved one live a fulfilling life free from alcohol and drug addiction. Below you can find out what to expect when you contact us for help.

Call us at (424) 327-4614 or fill out the form below and we will be in touch with you soon.

Send us a message below and we will reach out to you.
Design for Recovery Contact - Popup